Inflammatory bowel disease (IBD) affects the quantity and quality of mucins due to the reduction in the number of goblet cells. Alteration indifferent types of mucins and aberrant location may contribute to the underlying pathology by affecting the mucus barrier function or may instead be a response to inflammation. Mucin 9 (MUC9), also known as oviductin, is expressed in epithelial cells. No previous studies have explored the expression of MUC9 in patients with ulcerative colitis (UC). This is the first study to our best knowledge that investigates MUC9 gene expression in patients with UC.
Yamamoto-Furusho, J., Mendivil-Rangel, E., & Fonseca-Camarillo, G. (2012). Reduced expression of mucin 9 (MUC9) in patients with ulcerative colitis. Inflammatory Bowel Diseases, 18(3), E601. doi:10.1002/ibd.21920